| Home |
Projects |
Publications |
Collaborations |
Members |
Gallery |
| Protein Structure Prediction
We have developed a new method to predict the tertiary structure of
"new fold" proteins. This method is one of the few attempts to use an
all-atom physics-based energy function throughout all stages of the
minimization. It uses some knowledge from known proteins to guide the
search through the vast conformational spaceMore... |
||
 |
||
| ProteinShop
is
an interactive tool for manipulating protein structures. It was
designed to
quickly create a diverse set of initial configurations for a given
sequence of
amino acids. |
 |
|
|
||
 |
DockingShop is an integrated environment that permits interactive molecular docking by navigating a ligand or protein to an estimated binding site of a receptor with real-time graphical feedback of scoring factors as visual guides. | |
|
||
| POSE is
a graphical, interactive environment for the design, modeling, and
optimization of protein structures. POSE will support interactive,
user-driven monitoring and steering of a protein structure prediction
process but the resulting infrastructure will easily translate to
protein-protein interactions and RNA modeling. |
||
|
||
| Local
Minimizations Approaches for Local Minimizations
|
||