POSE - Protein Optimization Steering Environment

POSE is an interactive graphical environment for the design, modeling, and optimization of protein structures. It permits manipulation of protein structures with pinpoint control using concepts from robotics. Its features include: 1. automatic generation of 3D structures from sequence, 2. manipulation of parts of a protein with respect to its other parts without breaking its chemical structure, 3. real-time energy visualization to facilitate comparison and analysis of structures, 4. calculation of low-energy configurations by applying local optimizations, 5. automatic creation of a variety of low-energy beta-sheet configurations according to high-probability beta topologies and beta pairings.

News and  Announcements

POSE at ISMB 2005


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